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An efficient solvent-free synthesis of pyrido[2,3-d]pyrimidine derivatives utilizing lactic acid as green and eco-friendly catalyst

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Title An efficient solvent-free synthesis of pyrido[2,3-d]pyrimidine derivatives utilizing lactic acid as green and eco-friendly catalyst
 
Creator Safarzaei, Mohyeddin
Mollashahi, Ebrahim
Lashkari, Mojtaba
Maghsoodlou, Malek Taher
Hazeri, Nourallah
 
Subject Lactic acid
6-amino-1
3-dimethyluracil
aryl aldehyde
malononitrile
solvent-free conditions
 
Description 1368-1372
An efficient, solvent-free and one-pot procedure for the synthesis of pyrido[2,3-d]pyrimidine derivatives by condensation
of aromatic aldehydes, malononitrile and 6-amino-1,3-dimethyl uracil at 90°C catalyzed by lactic acid as an inexpensive,
biological and eco-friendly compound is described. The remarkable benefits of this procedure are green and environmentally
friendly reaction conditions, high yields, short reaction time, simple methodology and easy workup.
 
Date 2021-10-20T10:29:35Z
2021-10-20T10:29:35Z
2021-10
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58322
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(10) [October 2021]