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Enantioselective synthesis of bronchodilating agent (R)-Salmeterol<sup> #</sup>

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Title Enantioselective synthesis of bronchodilating agent (R)-Salmeterol #
 
Creator Ranganath, P L N
Anil, T
Narsaiah, A Venkat
 
Subject Enantioselective
amino alcohol
catecholamines
branchospasm
dihydroxylation
 
Description 1347-1352
Synthesis of β2-adrenoreceptor agonist bronchodilator (R)-Salmeterol has been described with good yields. The synthesis commenced from commercially available starting materials, 4-hydroxy benzaldehyde and phenylbutanoic acid. The features of the synthetic strategy are Wittig olefination and Sharpless asymmetric dihydroxylation.
 
Date 2021-10-20T11:02:15Z
2021-10-20T11:02:15Z
2021-10
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58325
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(10) [October 2021]