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Efficacy of manjistha and ginger powder in extending the lifespan of Drosophila melanogaster

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Title Efficacy of manjistha and ginger powder in extending the lifespan of Drosophila melanogaster
 
Creator Naorem, Anjana Singha
Thongatabam, Bijaya
Aggarwal, Prerna
Gupta, Gunjan
Raza, Amber
Yadav, Anamika
 
Subject Antioxidants
Drosophila
Ginger
Lifespan
Manjistha
Paraquat
 
Description 1048-1052
Ageing is a condition of deterioration of the physiological functions necessary for the survival and fertility over time.
Amongst the various factors that accelerate the ageing process, reactive oxygen species produced during normal metabolism
is one of the major contributors. In this study, we have evaluated the effect of manjistha and ginger on the lifespan of
Drosophila melanogaster. It was found that feeding manjistha and ginger can extend the lifespan of flies significantly,
unlike those fed on control media. Further, we demonstrated that manjistha was effective against paraquat-induced oxidative
stress. Upon paraquat treatment, mortality rate of 12% and 8% was observed in male and female flies respectively that were
reared on manjistha supplemented media whereas mortality of 100% and 92% were observed in male and female flies,
respectively when reared on control media. The present study suggests potential benefits on the longevity of the flies by the
dietary supplementation with ginger and manjistha, especially in the oxidative stress condition. These findings should be
further examined to identify active components present in these plant products that show its manifestation on the well-being
of the fly.
 
Date 2021-11-11T06:38:44Z
2021-11-11T06:38:44Z
2021-10
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/58442
 
Language en
 
Publisher CSIR-NIScPR, India
 
Source IJTK Vol.20(4) [October 2021]