<p class="TitleMain">Spiro-heterocycles: A convenient synthesis and antimicrobial activity of some 3-(5-aryl/aryloxymethyl-1,3,4-thiadiazol-2-yl)-spiro-cyclohexane-1',2-thiazolidin-4-ones</p><br /><p> </p>
Online Publishing @ NISCAIR
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Title Statement |
<p class="TitleMain">Spiro-heterocycles: A convenient synthesis and antimicrobial activity of some 3-(5-aryl/aryloxymethyl-1,3,4-thiadiazol-2-yl)-spiro-cyclohexane-1',2-thiazolidin-4-ones</p><br /><p> </p> |
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Added Entry - Uncontrolled Name |
Tiwari, Shailendra ; , university of Allahabad Begum, Kahkashan ; Department of Chemistry, Gandhi Faiz-E-Aam College, Shahjahanpur 242 001, India Ahmad, Akeel ; Department of Chemistry, Mirza Ghalib College, Gaya 823 001, India |
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Uncontrolled Index Term |
Substituted aryl/aryloxymethyl, 1,3,4-thiadiazole, spiro-cyclohexane, antimicrobial activity, antifungal activity |
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Summary, etc. |
<p class="Abstract" style="text-align: justify;"><span lang="EN-GB">A new series of novel 3-(5-aryl/aryloxy methyl-1,3,4-thiadiazol-2-yl)-spiro-cyclohexane-1<strong>'</strong>2-thiazolidin-4-ones have been synthesized from a common intermediate, in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) have been determined for the test compounds as well as for reference standards. Compounds <strong>3c, 3d, 6c </strong>and <strong>6d </strong>have shown good antibacterial activity where as compounds <strong>3a</strong>, <strong>3b</strong>, <strong>6a </strong>and <strong>6b </strong>have displayed better antifungal activity.</span></p><br /><p> </p> |
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Publication, Distribution, Etc. |
Indian Journal of Chemistry -Section B (IJC-B) 2021-11-18 10:12:23 |
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Electronic Location and Access |
http://op.niscair.res.in/index.php/IJCB/article/view/50058 |
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Data Source Entry |
Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 11 (2021): Indian Journal of Chemistry- Section-B, (IJCB) |
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Language Note |
en |
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Terms Governing Use and Reproduction Note |
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