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Addressing Iron and Zinc Micronutrient Malnutrition Through Nutrigenomics in Pearl Millet: Advances and Prospects

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Relation http://oar.icrisat.org/11927/
https://doi.org/10.3389/fgene.2021.723472
doi:10.3389/fgene.2021.723472
 
Title Addressing Iron and Zinc Micronutrient Malnutrition Through Nutrigenomics in Pearl Millet: Advances and Prospects
 
Creator Srivastava, R K
Satyavathi, C T
Mahendrakar, M D
Singh, R B
Kumar, S
Govindaraj, M
Ghazi, I A
 
Subject Pearl Millet
Food and Nutrition
 
Description Iron (Fe) and zinc (Zn) micronutrient deficiencies are significant health concerns, particularly
among the underprivileged and resource-poor people in the semi-arid tropics globally.
Pearl millet is regarded as a climate-smart crop with low water and energy footprints. It
thrives well under adverse agro-ecologies such as high temperatures and limited rainfall.
Pearl millet is regarded as a nutri-cereal owing to health-promoting traits such as high grain
Fe and Zn content, metabolizable energy, high antioxidant and polyphenols, high
proportion of slowly digestible starches, dietary fibers, and favorable essential amino
acid profile compared to many cereals. Higher genetic variability for grain Fe and Zn
content has facilitated considerable progress in mapping and mining QTLs, alleles and
genes underlying micronutrient metabolism. This has been made possible by developing
efficient genetic and genomic resources in pearl millet over the last decade. These include
genetic stocks such as bi-parental RIL mapping populations, association mapping panels,
chromosome segment substitution lines (CSSLs) and TILLING populations. On the
genomics side, considerable progress has been made in generating genomic markers,
such as SSR marker repository development. This was followed by the development of a
next-generation sequencing-based genome-wide SNP repository. The circa 1,000
genomes re-sequencing project played a significant role. A high-quality reference
genome was made available by re-sequencing of world diversity panel, mapping
population parents and hybrid parental lines. This mini-review attempts to provide
information on the current developments on mapping Fe and Zn content in pearl millet
and future outlook.
 
Publisher Frontiers Media
 
Date 2021-11
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://oar.icrisat.org/11927/1/Nutrigenomics%20in%20Pearl%20Millet%202021%20fgene-12-723472.pdf
Srivastava, R K and Satyavathi, C T and Mahendrakar, M D and Singh, R B and Kumar, S and Govindaraj, M and Ghazi, I A (2021) Addressing Iron and Zinc Micronutrient Malnutrition Through Nutrigenomics in Pearl Millet: Advances and Prospects. Frontiers in Genetics (TSI), 12 (723472). pp. 1-9. ISSN 1664-8021