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<p style="text-align: justify;">Bioactive constituents and <em>in vitro</em> antibacterial properties of <em>Petroselinum crispum</em> leaves, a common food herb in Saudi Arabia</p>

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Title Statement <p style="text-align: justify;">Bioactive constituents and <em>in vitro</em> antibacterial properties of <em>Petroselinum crispum</em> leaves, a common food herb in Saudi Arabia</p>
 
Added Entry - Uncontrolled Name Moni, Sivakumar Sivagurunathan; Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
Jabeen, Aamena ; Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
Sanobar, Syeda ; Department of Pharmacognosy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
ur Rehman, Zia ; Department of Pharmaceutical Chemistry, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
Alam, Md Shamsher; Department of Pharmaceutical Chemistry, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
Elmobark, Mohamed Eltaib; Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
 
Uncontrolled Index Term Alkaloids; Bioactive compounds; Fatty acids; Petroselinum crispum; Steroids; Terpenes.
 
Summary, etc. <p style="text-align: justify;">Herbs used as daily food additives are good resources for novel pharmaceutical agents. The study investigated the bioactive components of cold methanol maceration extract of <em>Petroselinum crispum </em>leaves. Spectral analysis with GC-MS and FT-IR studies demonstrated the presence of fatty acids and steroids, with fatty acids being the predominant components. GC-MS analysis showed the presence of 13-docosenoic acid methyl ester, (Z), cis-13-docosenoic acid, cis-11-eicosenoic acid methyl ester, 11-octadecenoic acid (stearate), methyl ester, hexadecanoic acid (palmitate) methyl ester, 15-tetracosenoic acid methyl ester (Z), cyclopentanone, 3,4-bis(methylene), and stigmastan-3-ol, 5-chloro- acetate. The FT-IR analysis of the fingerprint region displayed significant peaks at 3176.08, 2949, 2173, and 1018 cm<sup>-1</sup>, indicating the presence of aliphatic amino acids, steroidal compounds, isothiocyanates, polysaccharides, tannins and saponins. The cold methanolic extract (CME) of <em>P. crispum </em>produced a low spectrum of antibacterial effects against some screened human pathogenic bacteria and the phytochemical analysis of the extract revealed the presence of carbohydrates, steroids, and saponins. The extract exhibited a better spectrum of activity against Gram-negative bacteria than against Gram-positive bacteria.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2021-11-23 17:02:01
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/43084
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 3 (2021): September 2021
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/43084/465536962
 
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