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<p style="text-align: justify;">Preliminary phytochemical screening, thin layer chromatography profiling, and <em>in-vitro</em> antiurolithiatic activity of the leaves of <em>Ravenala madagascariensis </em>Sonn.</p>

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Title Statement <p style="text-align: justify;">Preliminary phytochemical screening, thin layer chromatography profiling, and <em>in-vitro</em> antiurolithiatic activity of the leaves of <em>Ravenala madagascariensis </em>Sonn.</p>
 
Added Entry - Uncontrolled Name S, Sakthi Priyadarsini; Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur 603203, Kanchipuram, Chennai, Tamil Nadu, India
Priya G, Mohana ; Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur 603203, Kanchipuram, Chennai, Tamil Nadu, India
R, Ramya ; Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur 603203, Kanchipuram, Chennai, Tamil Nadu, India
S, Lavanya ; Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur 603203, Kanchipuram, Chennai, Tamil Nadu, India
P R, Kumar ; Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur 603203, Kanchipuram, Chennai, Tamil Nadu, India
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Uncontrolled Index Term herbal medicine; natural products; urolithiasis
Calcium oxalate; In-vitro; Kidney stone; Ravenala madagascariensis; Turbidity method.
 
Summary, etc. <p style="text-align: justify;">Urolithiasis, the third most common disorder of the urinary tract is bundled with highly complex and unpredictably varied etiological factors. The undesirable adverse effects with current medications and the recurrence rate pose a major challenge in combating the disorder. <em>Ravenala madagascariensis</em> Sonn. has been used traditionally in treating kidney stone problems. The present study was aimed at investigating the antiurolithiatic activity of different extracts of the leaves of <em>R. madagascariensis</em>. Phytochemical screening carried out on the methanolic, hydromethanolic, and decoction extracts revealed the presence of alkaloids, carbohydrates, glycosides, cardiac glycosides, steroids, proteins, flavonoids, and quinones. Thin layer chromatography profiling of all three extracts was established. The turbidity method was carried out to evaluate <em>in-vitro</em> antiurolithiatic activity and the herbal formulation cystone was used as the standard drug. The results of the study showed that the decoction of <em>R. madagascariensis</em> exhibited excellent antiurolithiatic potential with an IC<sub>50</sub> value of 188.65 µg/mL in comparison with the methanolic (305.93 µg/mL) and hydromethanolic (306.83 µg/mL) extracts. Thus the findings of the study validate the claims of antiurolithiatic activity of <em>R. madagascariensis</em> that could be attributed to the presence of active phytoconstituents. Further studies are aimed at its formulation and development.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2021-11-23 17:02:01
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/37350
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 3 (2021): September 2021
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/37350/465515966
http://op.niscair.res.in/index.php/IJNPR/article/download/37350/465515968
 
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