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<p style="text-align: justify;">Larvicidal activity of <em>Acorus calamus</em> leaf extracts against the <em>Aedes aegypti</em> and <em>Culex quinquefasciatus</em></p>

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Title Statement <p style="text-align: justify;">Larvicidal activity of <em>Acorus calamus</em> leaf extracts against the <em>Aedes aegypti</em> and <em>Culex quinquefasciatus</em></p>
 
Added Entry - Uncontrolled Name Kirubakaran, Nithya ; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
Sathappan, Shanthi ; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
Sundaram, Janarthanan ; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
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Uncontrolled Index Term Acorus calamus; Aedes aegypti; Culex quinquefasciatus; Histopathology; Larvicidal activity.
 
Summary, etc. <p style="text-align: justify;">Mosquitoes are the important carriers of disease-causing pathogens responsible for serious health effects in humans. The vector control management mainly focuses on synthetic insecticides and their overuse creates resistance in mosquitoes. Henceforth, there is a need to develop insecticides that are effective and help in overcoming resistance development in mosquitoes. An attempt is made here to bring effective management of larval mosquitoes with herbal-based preparations since it is eco-friendly and causes no ill effects on humans. In this study, aqueous and solvent extracts of <em>Acorus calamus </em>leaves were tested for their anti-mosquito activity against third instar larvae of <em>Aedes aegypti </em>and <em>Culex quinquefasciatus</em>. Among the tested extracts, the crude hexane leaf extract of <em>A. calamus</em> showed the highest percentage of mortality with LC<sub>50 </sub>of 151.86 ppm and LC<sub>90 </sub>of 536.36 ppm against<em> A. aegypti</em> and LC<sub>50 </sub>of 174.70 ppm and LC<sub>90 </sub>of 696.73 ppm against <em>C. quinquefasciatus</em>. The treatment showed significant changes in the larval morphology such as damaged body parts, enlarged mid-gut, and lesions on the thoracic region. Similarly, histopathological analysis of treated larvae after 24 hours of treatment was observed with dislocations of cells, augmented nucleus, and ruptured epithelial cells. GC-MS analysis of the effective crude hexane leaf extract of<em> A. calamus </em>showed the presence of asarone to the level of 50.18% and that could have been thought to be insecticidal in nature which is probably responsible for the effective larval anti-mosquito activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2021-11-23 17:02:01
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/37681
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 3 (2021): September 2021
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/37681/465516925
http://op.niscair.res.in/index.php/IJNPR/article/download/37681/465516928
http://op.niscair.res.in/index.php/IJNPR/article/download/37681/465516930
 
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