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Benzothiazole derivatives of thiazole/ oxazole as potent antimicrobial agents

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Title Benzothiazole derivatives of thiazole/ oxazole as potent antimicrobial agents
 
Creator Kumar, Gajendra
 
Subject Antimicrobial
miconazole
imipenem
benzothiazole
oxazole
thiazole
 
Description 1607-1620
Non-steroid biologically active heterocyclic compounds (Z)-N'-(4-(2-(4-chlorophenyl)benzo[d]thiazol-3(2H)-yl) oxazol-2yl)-N-(4-substituted
phenylimino)-3-substituted-2,3-dihydrobenzo[d]oxazole-2-carboxamidine (4a-4h) and (Z)-N'- (4-(2-
(4-chlorophenyl)benzo[d]thiazol-3(2H)-yl)thiazol-2-yl)-N- (4-substituted phenylimino) -3-substituted-2-hydrobenzo[d]
thiazole-2-carboxamidine (4a’-4h’) have been synthesized, tested for their antimicrobial inhibiting potential and compared
with standard drugs Miconazole (antifungal) and Imipenem (antibacterial). Compound 4e’ is more potentially active than
other compounds and standard drugs. The structure configuration of newly synthesized compounds has been determined by
elemental analysis and various spectroscopic (IR, 1H and 13CNMR and GCMS) techniques.
 
Date 2021-12-15T10:36:56Z
2021-12-15T10:36:56Z
2021-12
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58607
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(12) [December 2021]