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New Mn(II)-coordination polymer based on flexible benzimidazol ligand: Crystal

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Title New Mn(II)-coordination polymer based on flexible benzimidazol ligand: Crystal
 
Creator Ni, Zhiming
Ding, Shuchen
Qu, Yuan
Yu, Hongbo
Xia, Junjie
 
Subject Coordination polymer
Osteosarcoma
RT-PCR
 
Description 1551-1556
In this study, a Mn(II)-based coordination polymer with the chemical composition of {[Mn(L)(TBTA)(H2O)2]ꞏH2O}n (1)
has been prepared by reacting Mn(OAc)2ꞏ2H2O with the flexible ligand 1,4-bis(5,6-dimethylbenzimidazol-1-yl)-2-butylene
in the aid of the carboxylic acid ligand tetrabromoterephthalic acid (H2TBTA) through the mixed-ligand method. Its
application value on osteosarcoma has been measured, and the internal principle is discussed simultaneously. The inhibitory
activity of the new compound on the multiplication of osteosarcoma cells is evaluated using the Cell Counting Kit-8
detection kit. The facilitation of the LKB1-mTORC1 signalling pathway is estimated via real-time RT-PCR.
 
Date 2021-12-16T09:56:58Z
2021-12-16T09:56:58Z
2021-12
 
Type Article
 
Identifier 0975-1017 (Online); 0971-4588 (Print)
http://nopr.niscair.res.in/handle/123456789/58616
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-A Vol.60A(12) [December 2021]