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Mixed ligand complex of monovalent copper with benzimidazole derivatives and alanine: Synthesis, characterization and antimicrobial studies

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Title Mixed ligand complex of monovalent copper with benzimidazole derivatives and alanine: Synthesis, characterization and antimicrobial studies
 
Creator Yadav, Poonam
Sharma, Shobhana
Kumari, Suman
Seema
Ranka, Mamta
 
Subject Mixed ligand complex
Azomethine
Benzimidazole
Alanine
Antibacterial
Antifungal
 
Description 1539-1544
xed ligand complexes of transition metal ions exhibit broad range of biological activities. Schiff bases containing
azomethine (C=N) group and amino acids are versatile compounds for design of ternary complexes. An attempt has been
made to synthesize novel copper(I) complex by the reaction of two ligands, 2-N-(4-methyl phenyl ethanimine)
benzimidazole [MPEIBI] as L1 and an amino acid Alanine as L2, and freshly prepared cuprous chloride solution in 1:1:1
molar ratio through conventional reflux method. The synthesized ligand and copper(I) complex are characterized by
elemental analysis, molecular weight determination, magnetic moment measurement, spectroscopic techniques. These
synthesized compounds were evaluated for antimicrobial studies against bacterial strains, B. subtilis, E. coli and fungal
pathogens, T. ressei, C. albicans. The Cu(I) complex has shown remarkable antibacterial and antifungal activity.
 
Date 2021-12-16T10:05:59Z
2021-12-16T10:05:59Z
2021-12
 
Type Article
 
Identifier 0975-1017 (Online); 0971-4588 (Print)
http://nopr.niscair.res.in/handle/123456789/58618
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-A Vol.60A(12) [December 2021]