<p style="text-align: justify;"><strong><span style="font-size: small;">Mixed ligand complex of monovalent Copper with benzimidazole derivatives and alanine: synthesis, characterization and antimicrobial studies</span></strong></p><p><strong><br /></strong></p><div id="_mcePaste" class="mcePaste" style="position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow: hidden;"><span style="font-size: 12.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN">Mixed ligand complexes of transition metal ions exhibit broad range of biological activities. Schiff bases containing azomethine (C=N) group and amino acids are versatile compounds for design of ternary complexes.</span><span style="font-size: 11.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN"> </span><span style="font-size: 12.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN">An attempt has been made to synthesize novel copper(I) complex by the reaction of two ligands, 2-N-(4-methyl phenyl ethanimine) benzimidazole [MPEIBI] as L<sub>1</sub> and an amino acid Alanine as L<sub>2</sub>, and freshly prepared Cuprous Chloride solution in 1:1:1 molar ratio through conventional reflux method. The synthesized ligand and Copper(I) complex are characterized by elemental analysis, molecular weight determination, magnetic moment measurement, spectroscopic techniques. These synthesized compounds were evaluated for antimicrobial studies against bacterial strains, <em>B. subtilis</em>, <em>E. coli</em> and fungal pathogens,hy <em>T. ressei</em>, <em>C. albicans</em>. The Cu(I) complex has shown remarkable antibacterial and antifungal activity. </span></div>
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Title Statement |
<p style="text-align: justify;"><strong><span style="font-size: small;">Mixed ligand complex of monovalent Copper with benzimidazole derivatives and alanine: synthesis, characterization and antimicrobial studies</span></strong></p><p><strong><br /></strong></p><div id="_mcePaste" class="mcePaste" style="position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow: hidden;"><span style="font-size: 12.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN">Mixed ligand complexes of transition metal ions exhibit broad range of biological activities. Schiff bases containing azomethine (C=N) group and amino acids are versatile compounds for design of ternary complexes.</span><span style="font-size: 11.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN"> </span><span style="font-size: 12.0pt; line-height: 115%; font-family: "Times New Roman",serif; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-IN; mso-fareast-language: EN-IN; mso-bidi-language: AR-SA;" lang="EN-IN">An attempt has been made to synthesize novel copper(I) complex by the reaction of two ligands, 2-N-(4-methyl phenyl ethanimine) benzimidazole [MPEIBI] as L<sub>1</sub> and an amino acid Alanine as L<sub>2</sub>, and freshly prepared Cuprous Chloride solution in 1:1:1 molar ratio through conventional reflux method. The synthesized ligand and Copper(I) complex are characterized by elemental analysis, molecular weight determination, magnetic moment measurement, spectroscopic techniques. These synthesized compounds were evaluated for antimicrobial studies against bacterial strains, <em>B. subtilis</em>, <em>E. coli</em> and fungal pathogens,hy <em>T. ressei</em>, <em>C. albicans</em>. The Cu(I) complex has shown remarkable antibacterial and antifungal activity. </span></div> |
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Added Entry - Uncontrolled Name |
RANKA, MAMTA ; UNIVERSITY OF RAJASTHAN, JAIPUR YADAV, POONAM ; UNIVERSITY OF RAJASTHAN, JAIPUR SHARMA, SHOBHANA ; UNIVERSITY OF RAJASTHAN, JAIPUR KUMARI, SUMAN ; UNIVERSITY OF RAJASTHAN, JAIPUR -, SEEMA ; UNIVERSITY OF RAJASTHAN, JAIPUR |
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Uncontrolled Index Term |
Synthetic and structural inorganic chemistry Mixed ligand complex; Azomethine; Benzimidazole; Alanine; Antibacterial; Antifungal. |
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Summary, etc. |
<span style="font-size: small;">Mixed ligand complexes of transition metal ions exhibit broad range of biological activities. Schiff bases containing azomethine (C=N) group and amino acids are versatile compounds for design of ternary complexes. An attempt has been made to synthesize novel copper(I) complex by the reaction of two ligands, 2-N-(4-methyl phenyl ethanimine) benzimidazole [MPEIBI] as L<sub>1</sub> and an amino acid Alanine as L<sub>2</sub>, and freshly prepared Cuprous Chloride solution in 1:1:1 molar ratio through conventional reflux method. The synthesized ligand and Copper(I) complex are characterized by elemental analysis, molecular weight determination, magnetic moment measurement, spectroscopic techniques. These synthesized compounds were evaluated for antimicrobial studies against bacterial strains, <em>B. subtilis</em>, <em>E. coli</em> and fungal pathogens,hy <em>T. ressei</em>, <em>C. albicans</em>. The Cu(I) complex has shown remarkable antibacterial and antifungal activity.</span> |
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Publication, Distribution, Etc. |
Indian Journal of Chemistry -Section A (IJCA) 2021-12-17 10:55:09 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJCA/article/view/51068 |
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Data Source Entry |
Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 60, ##issue.no## 12 (2021): INDIAN JOURNAL OF CHEMISTRY- SECTION A |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJCA/article/download/51068/465565492 |
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