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<p>Synthesis, antioxidant and antibacterial activities of quinoline incorporated 2,4,5-trisubstituted imidazole derivatives</p>

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Title Statement <p>Synthesis, antioxidant and antibacterial activities of quinoline incorporated 2,4,5-trisubstituted imidazole derivatives</p>
 
Added Entry - Uncontrolled Name Somashekara, B ; Department of Chemistry, University College of Science, Tumkur University, Tumkur 572 103, India Department of Chemistry, Smt. Indira Gandhi Government First Grade Women’s College, Sagar 577 401, India
Vijayakumar, Giriyapura R; Department of Chemistry, University College of Science, Tumkur University, Tumkur 572 103, India
 
Uncontrolled Index Term 2-Chloroquinoline, 2-hydroxyquinoline, antioxidant, antibacterial
 
Summary, etc. <p class="Abstract" style="text-align: justify;">A series of quinoline incorporated 2,4,5-trisubstituted imidazole derivatives (<strong>4a-h</strong> and <strong>5a</strong>-<strong>f</strong>) have been synthesized. The structures of the synthesized compounds have been established by FT-IR, <sup>1</sup>H NMR and mass spectral analysis. The prepared compounds have been evaluated for their <em>in vitro </em>antioxidant activity by DPPH method and antibacterial activity against <em>Bacillus subtilis</em>, <em>Escherichia coli</em>, <em>Bacillus megaterium</em> and <em>Salmonella typhi</em> bacterial strains at 500 µg/mL concentration. The compounds <strong>4a</strong>, <strong>4e</strong> and <strong>4d</strong> exhibit good antioxidant activity. Among the synthesized compounds, <strong>4a</strong> has shown significant antibacterial activity against all the three tested microorganisms.</p><p style="text-align: justify;"> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-12-20 11:23:07
 
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http://op.niscair.res.in/index.php/IJCB/article/view/38865
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 12 (2021): Indian Journal of Chemistry- Section-B, (IJCB)
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/38865/465520902
http://op.niscair.res.in/index.php/IJCB/article/download/38865/465523437
http://op.niscair.res.in/index.php/IJCB/article/download/38865/465523439
 
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