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Evaluation of bioceramic coated materials for orthopaedic applications

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Title Evaluation of bioceramic coated materials for orthopaedic applications
 
Creator Kala, K
Ganeasan, M Sundara
Balasubramani, V
Sasikumar, R
Kuppusamy, M R
Veerabadran, K M
Amala, K
Sridhar, T M
 
Subject EPD-Electrophoretic deposition
Hydroxyapatite
β-TCP-Tricalcium phosphate
2 diphenyl 1 picryl hydrazil compound (DPPH)
 
Description 637-644
Many surgical metals such as stainless steel, titanium, magnesium and its alloys have been extensively used for the
recovery of body structures in human beings. Corrosion is the major reason for failure in metallic implants, when the metal
comes in contact with the body fluids it releases metal ions into the surrounding tissues. This may even lead to the second
surgery which can be eradicated by the surface modification of the implant with bioceramics using coating techniques. The
present work involves the development of coatings on the surface of 316L SS type of stainless steel using a biphasic mixture
of bio ceramics HAP/β-TCP in ratio of 7.5:2.5 by electrophoretic deposition (EPD) from a suspension of ethanol. The
presence of biphasic coating imparts the property of both bioactivity and bioresorbability to the implant with good
adherence of the coatings in body fluids. These coatings provide corrosion resistance and also favour new bone growth.
Further, the biocompatibility of these materials can be evaluated by in-vitro assay. This includes cytotoxicity tests carried
out with normal cell line (Vero cell line) and cancerous cell line (HEP II cell Line). The coated samples have been tested for
their biochemical nature using DPPH (2,2 diphenyl 1 picryl hydrazil compound) activity to confirm whether the coated
implant is suitable for cancerous patients with its antioxidant property which helps to trap the free radicals.
 
Date 2021-12-24T05:01:17Z
2021-12-24T05:01:17Z
2021-09
 
Type Article
 
Identifier 0975-0991 (Online); 0971-457X (Print)
http://nopr.niscair.res.in/handle/123456789/58677
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJCT Vol.28(5) [September 2021]