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Anti-oxidant activity of compounds and fractions of Manilkara hexandra (Roxb) bark

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Title Anti-oxidant activity of compounds and fractions of Manilkara hexandra (Roxb) bark
 
Creator Annamalai, T
Prince, A A M.
 
Subject Anti-oxidant
Manilkara hexandra
Oral diseases
Plant phenols
S.mutans
 
Description 547-555
Isolation of a protein mixture having IC50 of 60µg/mL against Streptococcus mutans from the methanol extract of
bark of Manilkara hexandra (Roxb) along with six plants phenols Catechin, Catecol, Gallic acid, Phloroglucinol,
Quercetin and Rutin has been reported. Where in phenolic constituents of the bark has been reported for the first time
and the isolated compounds having moderate activity against S.mutans.In this work, the anti-oxidant activity of these
pure compounds and fractions has been studied and its relevance in oral care is established. Comparative anti-oxidant
activity of all the six compounds along with the crude extract and fractions have been assessed using eight different assay
protocols. The results indicate that twice daily tooth cleaning with the bark can provide basic oral disease protection and
thereby assuring several health benefits. Synergistic activity of the phenolic constituents along with the protein and other
constituentsmight be a reasonable scientific explanation for the folklore use of the plant as one of the prescription for
oral diseases.
 
Date 2021-12-24T05:58:44Z
2021-12-24T05:58:44Z
2021-09
 
Type Article
 
Identifier 0975-0991 (Online); 0971-457X (Print)
http://nopr.niscair.res.in/handle/123456789/58694
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJCT Vol.28(5) [September 2021]