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<p>A new Ln(III) coordination polymer constructed from a hexadentate triazine ligand: Treatment activity and nursing value for ovarian cancer</p>

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Title Statement <p>A new Ln(III) coordination polymer constructed from a hexadentate triazine ligand: Treatment activity and nursing value for ovarian cancer</p>
 
Added Entry - Uncontrolled Name Wang, Xiaoqin Wang ; Department of Gynaecology, Ningbo Women's and Children's Hospital, Ningbo, Zhejiang, China
Zhang, Duoyi ; Department of Gynaecology, Ningbo First Hospital, Ningbo, Zhejiang, China
Li, Xin ; Department of Gynaecology, Ningbo Women's and Children's Hospital, Ningbo, Zhejiang, China
Wang, Qiming ; Department of Gynaecology, Ningbo Women's and Children's Hospital, Ningbo, Zhejiang, China
 
Uncontrolled Index Term Coordination polymer, Ovarian cancer, RT-PCR
 
Summary, etc. <p style="text-align: justify;">In this current paper, a 3D lanthanide (Ln) coordination polymer (CP), compound <strong>1 </strong>with a chemical formula of [(NH<sub>2</sub>(Me)<sub>2</sub>)]<sub>6</sub>·[Gd<sub>3</sub>(TATAT)<sub>2</sub>(μ<sub>2</sub>-O)<sub>1.5</sub>]·3EtOH·7.5H<sub>2</sub>O is synthesized with<em> </em>the reaction between GdCl<sub>3</sub>·6H<sub>2</sub>O and 5,5′,5′′-(1,3,5-triazine-2,4,6-triyltriimino)tris(azanediyl) triisophthalate (H<sub>6</sub>TATAT). Its treatment activity and nursing value against ovarian cancer is tested and the associated mechanism is analyzed simultaneously. At first, the CCK-8 detection is implemented to determine the suppression activity of<strong> </strong>compound<strong> 1 </strong>against the cell viability of ovarian cancer after treated via our compound. Furthermore, in order to detect the relative expression for the estrogen receptor on cells of ovarian cancer, real time RT-PCR is carried out.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-02-02 16:02:00
 
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http://op.niscair.res.in/index.php/IJC/article/view/60050
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 1 (2022): Indian Journal of Chemistry-(IJC)
 
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