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Antimicrobial, antioxidant and anticancer potential of Streptomyces species isolated from the rhizosphere of Avicennia marina (Forssk.) Vierh.

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Title Antimicrobial, antioxidant and anticancer potential of Streptomyces species isolated from the rhizosphere of Avicennia marina (Forssk.) Vierh.
 
Creator Abdallah, Omnia M
Tolba, Sahar TM
Mohamed, Mohamed Ragaa
 
Subject Actinobacteria
Antibacterial
Anticancer
Antimicrobial
Antioxidant
Grey or White mangrove
 
Description 81-90
Free radicals produced through biochemical processes cause dangerous health problems due to their oxidative effect on
cellular proteins and lipids. There is an urgent need for natural antioxidants to be used as therapeutic agents. Streptomyces
are known as producers for antioxidants, in this study, two Streptomyces species were isolated from the rhizosphere soil of
mangrove tree Avicennia marina (Forssk.) Vierh. The isolates were identified by conventional as well as molecular methods
as Streptomyces atrovirens (MS5) and S. labedae (MR15). The ethyl acetate extracts of cell free production broth medium
of the two isolates demonstrated potent biological activities against Gram positive and Gram negative bacteria and Candida
albicans. Moreover, a radical scavenging activity in DPPH assay with significant inhibition percentage of 62 and 78%,
respectively, was recorded. The IC50 values were 3000 and 241 μg/mL (P
 
Date 2022-01-31T11:24:17Z
2022-01-31T11:24:17Z
2022-02
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscair.res.in/handle/123456789/59008
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.60(02) [Feb 2022]