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Development of quality standards of Triphala Kwatha churna with its ingredients through HPTLC and mass spectroscopy

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Title Statement Development of quality standards of Triphala Kwatha churna with its ingredients through HPTLC and mass spectroscopy
 
Added Entry - Uncontrolled Name Das, Manosi ; Central Ayurveda Research Institute for Drug Development, CCRAS, Kolkata 700091
Singh, Ravindra ; Central Council for Research in Ayurvedic Sciences, Ministry of Ayush, New Delhi 110 058, India
Bolleddu, Rajesh ; Central Ayurveda Research Institute for Drug Development, 4 Minerva Road, CN Block, Sector V, Bidhannagar 700 091, Kolkata, India
Banerji, Avijit ; Central Ayurveda Research Institute for Drug Development, 4 Minerva Road, CN Block, Sector V, Bidhannagar 700 091, Kolkata, India
Roy, Souvik ; Central Instrumentation Facility, Bose Institute, Kolkata 700 091, India
Hazra, Jayram ; Central Ayurveda Research Institute for Drug Development, 4 Minerva Road, CN Block, Sector V, Bidhannagar 700 091, Kolkata, India
Central Council for Research ih Ayurvedic Sciences
 
Uncontrolled Index Term Triphala Kwatha churna, HPTLC finger-print, Mass spectroscopy, Physicochemical parameters, Phytochemical screening, Quality standards
 
Summary, etc. In recent years there has been rapid growth in the field of herbal medicine. Drugs belonging to Asian traditional systems of medicine are accepted universally only after standardisation. It is therefore, very important to develop essential techniques for standardisation of herbal drugs. The present study has focused on development of quality standards of Triphala Kwatha churna under WHO/API guidelines along with HPTLC and mass spectroscopy. This polyherbal Kwatha churna is used to treat constipation and other gastric disorders. In this study, an in-house prepared Triphala Kwatha churna was botanically and chemically standardised by HPTLC and mass spectroscopic studies with the reference standard gallic acid. The botanical standardisation of the above formulation was done by evaluation of macroscopic and microscopic studies of the powder formulation along with its ingredients. Physicochemical parameters like LOD, ash value, acid insoluble ash, water and alcohol extractives were determined. Safety parameters, viz., heavy metals, microbial content, specific pathogens, pesticide residue and aflatoxins detection have been also estimated. The results obtained in the present study defining quality control parameters help to develop the quality standards of Triphala Kwatha churna formulation. The HPTLC fingerprint profiling of the formulation along with its ingredients complies with the reference standards gallic acid. This observation is also found in Mass Spectroscopic study of the methanolic extract of the formulation with this reference standard. Preliminary phytochemical screening test revealed the presence of bioactive constituents including phenols, flavonoids, tannins and carbohydrates.
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2022-02-09 16:35:14
 
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http://op.niscair.res.in/index.php/IJTK/article/view/41049
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 21, ##issue.no## 1 (2022): Indian Journal of Traditional Knowledge
 
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