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<p>Synthesis and antimicrobial activity of novel benzo[4', 5']-imidazo[1',2':1,2]pyrrolo[3,4-<em>b</em>]isoxazolo[4,5-<em>e</em>]pyridines</p>

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Title Statement <p>Synthesis and antimicrobial activity of novel benzo[4', 5']-imidazo[1',2':1,2]pyrrolo[3,4-<em>b</em>]isoxazolo[4,5-<em>e</em>]pyridines</p>
 
Added Entry - Uncontrolled Name Prasoona, G ; Department of Chemistry, Kakatiya University, Hanamkonda 506 009, India Government Degree College, Narsampet, Warangal 506 132, India
Kishore, B ; Department of Chemistry, Kakatiya University, Hanamkonda 506 009, India
Brahmeshwari, G ; Department of Chemistry, Kakatiya University, Hanamkonda 506 009, India
 
Uncontrolled Index Term 1-(Prop-2-yn-1-yl)-1H-benzo[d]imidazo-2-carbaldehydes, condensation, intramolecular Povarov reaction, benzo[4',5']imidazo[1',2':1,2]pyrrolo[3,4-b]isoxazolo[4,5-e] pyridines, antimicrobial activity
 
Summary, etc. <p class="Abstract" style="text-align: justify;">Synthesis of novel benzo [4',5'] imidazo [1',2':1,2] pyrrolo [3,4-<em>b</em>] isoxazolo [4,5-<em>e</em>] pyridines <strong>8</strong> has been achieved by reaction of 1-(prop-2-yn-1-yl)-1<em>H</em>-benzo [<em>d</em>] imidazo-2-carbaldehydes <strong>5</strong> with 5-amino -3-methylisoxazole <strong>6</strong> in presence of InCl<sub>3</sub> in CH<sub>3</sub>CN media, followed by reaction of imine <strong>7</strong> with BF<sub>3</sub>.Et<sub>2</sub>O in DCE at 80°C. The newly synthesized title compounds <strong>8</strong> have been evaluated for their <em>in vitro</em> antimicrobial activity. Compounds <strong>8</strong> exhibit potent antimicrobial activity compared to that of standard drugs.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-02-21 00:00:00
 
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http://op.niscair.res.in/index.php/IJC/article/view/60714
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 2 (2022): Indian Journal of Chemistry-(IJC)
 
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