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Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam

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Title Statement Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam
 
Added Entry - Uncontrolled Name DAS, LEENA ; College of Veterinary Science,AAU
SHARMA, KRISHNA ; COLLEGE OF VETERINARY SCIENCE, ASSAM AGRICULTURAL UNIVERSITY, KHANAPARA, GUWAHATI
BORAH, PROBODH ; COLLEGE OF VETERINARY SCIENCE, ASSAM AGRICULTURAL UNIVERSITY, KHANAPARA, GUWAHATI
BARMAN, NAGENDRA NATH; COLLEGE OF VETERINARY SCIENCE, ASSAM AGRICULTURAL UNIVERSITY, KHANAPARA, GUWAHATI
KALITA, DHRUBA JYOTI; COLLEGE OF VETERINARY SCIENCE, ASSAM AGRICULTURAL UNIVERSITY, KHANAPARA, GUWAHATI
HUSSAIN, IFTIKAR ; BIOTECHNOLOGY INDUSTRY RESEARCH ASSISTANCE COUNCIL(DBT-BIRAC), NEW DELHI
DEVI, BHANITA ; ANIMAL AND FISHERIES RESOURCES, GOVERNMENT OF BIHAR,
State Biotech Hub, Assam funded by DBT, GOVT. OF INDIA
 
Uncontrolled Index Term Cytokines; Interleukins; Livestock; Oropharyngeal fluid
 
Summary, etc. Foot and mouth disease (FMD), one of the most contagious diseases of animals, affects different host species including wild animals. Asymptomatic FMD recovered animals may remain as carrier, which may be threat to other healthy animals. Hence, it is necessary to monitor the carrier status of the FMD recovered animals to effectively prevent further spread of the disease. Out of all the seven serotypes of FMD, O serotype is most commonly found in livestock. Therefore, in the present study, we chose to detect serotype ‘O’ in oropharyngeal fluid (OP) and to quantify cytokines, viz. IL-1α, IL-1β and IL-2. A total of 30 OP fluids and 30 blood samples were collected from 10 animals (1 in-contact healthy animal) for 3 months post infection. FMD O serotype could be detected in all the animals (100%). The RQ values were found to be 0.014 to 63.118 and 0.162 to 46.889 for IL-1α and IL-1β genes respectively, while insignificant RQ values were obtained for IL-2. In the second and third months, two animals showed down regulation for IL-1α gene, while IL-1β and IL-2 genes were down regulated in 7 animals and in all 10 animals, respectively for all the three months.
 
Publication, Distribution, Etc. Indian Journal of Experimental Biology (IJEB)
2022-03-03 16:32:24
 
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http://op.niscair.res.in/index.php/IJEB/article/view/34804
 
Data Source Entry Indian Journal of Experimental Biology (IJEB); ##issue.vol## 60, ##issue.no## 03 (2022): IJEB [March 2022]
 
Language Note en
 
Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJEB/article/download/34804/465599902