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Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam

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Title Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam
 
Creator Das, Leena
Sarmah, Krishna
Borah, Probodh
Barman, NN
Kalita, DJ
Hussain, Iftikar
Devi, Bhanita
 
Subject Cytokines
Interleukins
Livestock
Oropharyngeal fluid
 
Description 200-206
Foot and mouth disease (FMD), one of the most contagious diseases of animals, affects different host species including
wild animals. Asymptomatic FMD recovered animals may remain as carrier, which may be threat to other healthy animals.
Hence, it is necessary to monitor the carrier status of the FMD recovered animals to effectively prevent further spread of the
disease. Out of all the seven serotypes of FMD, O serotype is most commonly found in livestock. Therefore, in the present
study, we chose to detect serotype ‘O’ in oropharyngeal fluid (OP) and to quantify cytokines, viz. IL-1α, IL-1β and IL-2.
A total of 30 OP fluids and 30 blood samples were collected from 10 animals (1 in-contact healthy animal) for 3 months
post infection. FMD O serotype could be detected in all the animals (100%). The RQ values were found to be 0.014 to
63.118 and 0.162 to 46.889 for IL-1α and IL-1β genes respectively, while insignificant RQ values were obtained for IL-2. In
the second and third months, two animals showed down regulation for IL-1α gene, while IL-1β and IL-2 genes were down
regulated in 7 animals and in all 10 animals, respectively for all the three months.
 
Date 2022-03-04T07:23:48Z
2022-03-04T07:23:48Z
2022-03
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscair.res.in/handle/123456789/59287
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.60(03) [Mar 2022]