<em>Penicillium citrinum </em>Thom: A potential antihyperglycemic endophyte from<em> Gymnema sylvestre</em>
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Title Statement |
<em>Penicillium citrinum </em>Thom: A potential antihyperglycemic endophyte from<em> Gymnema sylvestre</em> |
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Added Entry - Uncontrolled Name |
G M, Vidyasagar ; Department of Botany, Gulbarga University, Kalaburagi 585106, Karnataka, India Naaz, Syeda Qizra; Department of Botany, Gulbarga University, Kalaburagi 585106, Karnataka, India Ahmed, MD Liyakat; Luqman College of Pharmacy, Kalaburagi 585102, Karnataka, India Babanagre, Shankaravva ; Department of Botany, NMKRV Degree College for Women, Jayanagar 1st Block, Bangalore 560041, Karnataka, India M K, Sangeeta ; Department of Botany, Gulbarga University, Kalaburagi 585106, Karnataka, India V, Ambika ; Department of Botany, Gulbarga University, Kalaburagi 585106, Karnataka, India National Fungal Culture Collection of India (NFCCI), Agharkar Research Institute, Pune |
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Uncontrolled Index Term |
Antihyperglycemic activity; Endophytes; Gymnema sylvestre; Penicillium citrinum Thom; Phytochemicals. |
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Summary, etc. |
<p style="text-align: justify;">Endophytic fungi producing bioactive compounds from medicinal plants have enormous applications as, antibiotics, anti-parasitic, agrochemical, antioxidants and anticancer agents. In the present research, aimed to investigate the qualitative and quantitative analysis of secondary metabolites of an endophyte isolated from <em>Gymnema sylvestre </em>and to evaluate its antidiabetic potential. The frequently occurring fungal isolate VSQ-11 was selected for in detailed research work. Based on the morphological and molecular characteristics, the isolate was identified as <em>Penicillium citrinum Thom</em>. Myco-chemical studies exhibit the maximum presence of flavonoids (4 mg/g) followed by phenols (1 mg/g), tannins (1.178 mg/g), saponins (1.175 mg/g), steroids (0.96 mg/g), glycosides (0.6 mg/g) and alkaloids (0.34 mg/g) in crud fungal extract. The Albino mice treated with fungal ethyl acetate extract (250 mg/kg body weight) has shown a reduction in blood glucose level as compared to the negative control group.</p> |
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Publication, Distribution, Etc. |
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] 2022-03-15 11:16:10 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJNPR/article/view/33000 |
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Data Source Entry |
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 4 (2021): DECEMBER 2021 |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJNPR/article/download/33000/465502244 |
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Terms Governing Use and Reproduction Note |
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