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High resolution-mass spectrometry (HR-MS) analysis of <em>Bryonia laciniosa </em>L<em>.</em>

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Title Statement High resolution-mass spectrometry (HR-MS) analysis of <em>Bryonia laciniosa </em>L<em>.</em>
 
Added Entry - Uncontrolled Name M, Shashikala ; Department of Pharmacognosy, Gokaraju Rangaraju College of Pharmacy, Hyderabad 500090, India
Shah, Mamta B.; Department of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad 380009, India
Sophisticated Analytical Instrument Facility (SAIF), Indian Institute of Technology-Bombay, Mumbai (India)
 
Uncontrolled Index Term Bryonia laciniosa; HR-MS:
Bryonia laciniosa L.; HR-MS analysis; Sterol-rich petroleum ether extract.
 
Summary, etc. <p style="text-align: justify;"><em>Bryonia laciniosa </em>L. (Family: Cucurbitaceae) is commonly known as ‘Shivlingi’ and is a highly valued medicinal plant in Ayurveda and Homeopathy systems of medicine particularly as a remedy for infertility. In the present study, sophisticated, highly reliable, and sensitive high resolution-mass spectrometry (HR-MS) was carried out for the determination of chemical constituents present in <em>B. laciniosa</em>. Phytochemical screening of methanolic extract showed the presence of saponins, sterols, triterpenoids, flavonoids, alkaloids, phenolic compounds, and tannins. TLC of sterol-rich petroleum ether extract (SRPE) produced six major spots on precoated silica gel GF<sub>254</sub>,<sub> </sub>using toluene: methanol (96:04 v/v) as mobile phase. The spots showed green, purple, light purple to violet colour spots in the Rf range of 0.2-0.91, after derivatization with the anisaldehyde-sulphuric acid reagent. Further, based on TLC, HR-MS analysis of SRPE was performed for the identification of phytoconstituents, at positive ESI (electron spray ionisation) mode. It indicated the presence of a total of 30 compounds including short fragments of peptides. The major compounds predicted in HR-MS: Q(quadrupole)-TOF(time-of-flight)-MS, as per METLIN database, were swietenine, ergosterol acetate, 4, 4, dimethyl-14α-formyl-5α-cholesta-8,24-dien-3β-ol, L-olivosyl-oleandolide, mitoxantrone, isogedunin, 3S-aminodeconoic acid, and nisoldipine.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2022-03-15 11:16:10
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/41652
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 4 (2021): DECEMBER 2021
 
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