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Green synthesis and antibacterial/fungal studies of two new Schiff base derived from 4-(imidazol-1-yl)benzaldehyde

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Title Green synthesis and antibacterial/fungal studies of two new Schiff base derived from 4-(imidazol-1-yl)benzaldehyde
 
Creator Feng, Xiaojun
Wang, Fangkuo
Liu, Weiguo
Dong, Huaze
 
Subject Schiff base
antibacterial activity
crystal structure
 
Description 298-304
This study synthesizes two new Schiff bases, (E)-1-(4-1H-imidazol-1-yl)phenyl)-N-(o-tolyl)methanimine and (E)-1-(4-(1Himidazol-
1-yl)phenyl)-N-(m-tolyl)methanimine through condensation reaction between 4-(imidazol-1-yl)benzaldehyde and
2-toluidine/o-toluidine, respectively. FT-IR, X-ray diffraction and 1H NMR spectroscopy have been carried out to
characterize the structure of the products. Through antibacterial/ antifungal activity tests performed using 8 kinds of
bacteria/fungus, it is found that the both of the two Schiff bases can suppress the growth of Staphylococcus, Bacillus subtilis
and Salmonella, showing good potential as antibacterial drug.
 
Date 2022-03-23T10:17:24Z
2022-03-23T10:17:24Z
2022-03
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscair.res.in/handle/123456789/59341
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.61(03) [March 2022]