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Polylactic acid and lanolin based nanofibrous structures for wound management application

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Field Value
 
Title Polylactic acid and lanolin based nanofibrous structures for wound management application
 
Creator Uzun, Muhammet
Oymak, Hüseyin
 
Subject Lanolin
Medical textiles
Nanostructures
Polylactic acid
Wound dressings
Wood oil
 
Description 105-115
Polylactic acid (PLA) polymer and wool oil (lanolin) have been used to develop nanostructures for wound dressing management. Lanolin has been extracted from raw wool surfaces and used as a by-product in wide range of pharmaceutical areas. Different solutions with varying concentration of the PLA/lanolin and sodium alginate/lanolin solutions have been prepared and then nanostructures are developed using electrospinning method. The developed structures are aimed to use as smart wound dressings. During the production stage, the parameters of the electrospinning process have been changed to develop the optimum structures. The effect of solution concentrations on the applied voltage and the distance between the pipette tip and the collector is highlighted. The spinnability of lanolin is the main objectives of this study and the PLA/lanolin nanostructures are designed and manufactured successfully. The essential test methods have been performed to measure the usability of the produced materials as wound dressings. These are liquid absorption capacity, horizontal/vertical wicking, SEM, degradation, pH, antibacterial assay, and tensile properties. From the tested parameters, it is obviously found that the use of PLA/lanolin as wound dressing is suitable according to initial in vitro test results.
 
Date 2022-03-24T10:02:38Z
2022-03-24T10:02:41Z
2022-03-24T10:02:38Z
2022-03-24T10:02:41Z
2022-03
 
Type Article
 
Identifier 0975-1025 (Online); 0971-0426 (Print)
http://nopr.niscair.res.in/handle/123456789/59355
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJFTR Vol.47(1) [March 2022]