Record Details

Antibacterial and wound healing efficacy of Chromolaena odorata treated dressings

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Antibacterial and wound healing efficacy of Chromolaena odorata treated dressings
 
Creator Resmi, G
Amsamani, S
 
Subject Antibacterial textiles
Bioactive wound dressings
Chromolaena odorata
Cytotoxicity
In vivo wound healing
Spun lace viscose
 
Description 78-86
This paper reports the characteristics of viscose fabric treated with the extracts of Chromolaena odorata, traditionally
used for healing the wounds. C. odorata extracts (5%) are nano-sprayed and applied on spun lace viscose fabric using an
ultrasonic atomiser and antibacterial competence is optimised for S. aureus and E. coli. The wound healing potential of the
C. odorata treated dressing and histopathological analysis of the wound tissues have been studied in vivo on Albino Wistar
rats and compared with wound without any dressings, chitosan treated dressing, chitosan and C. odorata treated dressing
along with the commercial silver bandage. The FTIR analysis of the phytochemicals finished fabric indicates the presence of
phenolic group. Cytotoxicity test reveals 22% cytotoxicity and 78% cell viability with mild toxicity. Shelf life discloses the
decrease in antibacterial efficiency after third and fourth week. Curing of C. odorata extracts treated fabric inversely affects
the antibacterial efficiency, and sterilisation reports 46.7% E.coli reduction after one hour. The fabricated wound dressings
are found to have good wound healing efficiency as compared to commercial silver bandage. The histopathological analysis
reveals complete healing of wounds after 21 post wound healing days. The study proves that the phytochemicals can be
imparted on spun lace viscose fabric for antibacterial and wound healing application to a certain period of time.
 
Date 2022-03-24T10:56:06Z
2022-03-24T10:56:06Z
2022-03
 
Type Article
 
Identifier 0975-1025 (Online); 0971-0426 (Print)
http://nopr.niscair.res.in/handle/123456789/59358
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJFTR Vol.47(1) [March 2022]