Record Details

Survivability of Penaeus monodon during white spot syndrome virus infection and its correlation with immune related genes

CMFRI Repository

View Archive Info
 
 
Field Value
 
Relation http://eprints.cmfri.org.in/9367/
 
Title Survivability of Penaeus monodon during white spot syndrome virus infection and its
correlation with immune related genes
 
Creator Joseph, Jeswin
Anju, A
Thomas, P C
Paulton, M P
Vijayan, K K
 
Subject Fish Diseases
Fish Genetics
 
Description At present the most common andmost devastating disease of shrimp is caused by the white spot syndrome virus
(WSSV), which has spread throughout the world mainly by the different species of crustaceans carrying the
virus. Although considerable progress has been made in the molecular characterisation of WSSV, little
information is available on shrimp geneswhich are involved inWSSV infection. To develop a better understanding
of the shrimp antiviral defences and possibly develop newcontrolmeasures forWSSV, differential expression
of immune related genes in haemocytes was studied. Gene expression of penaeidins, crustin, lysozyme, C-type
lectin, prophenoloxidase-1, prophenoloxidase-2 and haemocyanin in Penaeus monodon following experimental
infection withWSSV was studied and the time-dependent pattern was determined. The study showed the general
trend of upregulation of five (penaeidins, lysozyme, C-type lectin, prophenoloxidase-1, prophenoloxidase-2)
of the seven genes at the early hours of infection. Animals surviving beyond 84 h following WSSV infection
showed higher levels of expression of genes encoding lysozyme, C-type lectin, penaeidins, prophenoloxidase-1
and prophenoloxidase-2 than those animals which died before 60 h, indicating a genetic basis in disease resistance.
The gene expression level can therefore be used as a biomarker for selecting broodstocks for better resistance
to WSSV infection, thus promising a role in the fight against WSSV along with other management
measures.
 
Date 2013
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://eprints.cmfri.org.in/9367/1/149.pdf
Joseph, Jeswin and Anju, A and Thomas, P C and Paulton, M P and Vijayan, K K (2013) Survivability of Penaeus monodon during white spot syndrome virus infection and its correlation with immune related genes. Aquaculture, 380 (383). pp. 84-90.