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Pueraria tuberosa: A Review on Traditional Uses, Pharmacology, and Phytochemistry

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Pueraria tuberosa: A Review on Traditional Uses, Pharmacology, and Phytochemistry
 
Creator Bharti, Ram
Chopra, Bhupinder Singh
Raut, Sachin
Khatri, Neeraj
 
Subject QR Microbiology
 
Description Pueraria tuberosa (Roxb. ex Willd.) DC. (Fabaceae), also known as Indian Kudzu (vidari kand), is a perennial herb distributed throughout India and other Asian countries. Traditionally, tuber and leaves of this plant have extensively been reported for nutritional and medicinal properties in Ayurveda as well as in Chinese traditional practices. The objective of the present review is to compile and update the published data on traditional uses, pharmacological potential, and phytochemistry of compounds isolated from the plant Pueraria tuberosa. P. tuberosa extracts and its purified compounds possess multiple activities such as anticancer, anticonvulsant, antidiabetic, antifertility, anti-inflammatory, antioxidant, anti-stress, antiulcerogenic, cardioprotective, hypolipidemic, hepatoprotective, immunomodulatory, nephroprotective, nootropic, neuroprotective, and wound healing. Tuber and leaf extracts of P. tuberosa contain several bioactive constituents such as puerarin, daidzein, genistein, quercetin, irisolidone, biochanin A, biochanin B, isoorientin, and mangiferin, which possess an extensive range of pharmacological activities. The extensive range of pharmacological properties of P. tuberosa provides opportunities for further investigation and presents a new approach for the treatment of ailments. Many phytochemicals have been identified and characterized from P. tuberosa; however, some of them are still unexplored, and there is no supporting data for their activities and exact mechanisms of action. Therefore, further investigations are warranted to unravel the mechanisms of action of individual constituents of this plant.
 
Publisher Frontiers
 
Date 2021-01-27
 
Type Article
PeerReviewed
 
Relation https://www.frontiersin.org/articles/10.3389/fphar.2020.582506/full
http://crdd.osdd.net/open/2733/
 
Identifier Bharti, Ram and Chopra, Bhupinder Singh and Raut, Sachin and Khatri, Neeraj (2021) Pueraria tuberosa: A Review on Traditional Uses, Pharmacology, and Phytochemistry. FRONTIERS IN PHARMACOLOGY, 11.