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<p style="text-align: justify;">Design, synthesis and biological potential of some isoxazole and hydroxypyrimidine derivatives containing pyrido [2,3-<em>d</em>] pyrimidine nucleus <em>via</em> chalcone series</p>

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Title Statement <p style="text-align: justify;">Design, synthesis and biological potential of some isoxazole and hydroxypyrimidine derivatives containing pyrido [2,3-<em>d</em>] pyrimidine nucleus <em>via</em> chalcone series</p>
 
Added Entry - Uncontrolled Name Tandel, Hemanshu T; Department of Chemistry, Veer Narmad South Gujarat University, Surat 395 007, India
Patel, Saurabh K; Department of Chemistry, Veer Narmad South Gujarat University, Surat 395 007, India
 
Uncontrolled Index Term Isoxazole, hydroxypyrimidine, synthesis, biological activity
 
Summary, etc. <p class="Abstract" style="text-align: justify;"><span lang="EN-GB">Synthesis of 4-(2,4-dimethoxy-6-(5-substitutedphenylisoxazol-3-yl) pyrido[2,3-<em>d</em>] pyrimidin-7-yl)morpholine has been carried out by reaction of (E)-3-(2,4-dimethoxy-7-morpholinopyrido[2,3-<em>d</em>]pyrimidin-6-yl)-1-substituted phenylprop-2-en-1-one with hydroxylamine hydrochloride analogue to get the compounds <strong>8a-f</strong> and synthesis of 4-(2,4-dimethoxy-7-morpholinopyrido[2,3-<em>d</em>]pyrimidin-6-yl)-6-phenylpyrimidin-2-ol with urea to get various hydroxypyrimidine of the studied analogue to get the compounds <strong>9a-f</strong>. Structures of all the newly synthesized compounds have been characterized by instrumental method. Representative compounds of the synthesized product series have been tested and evaluated as antimicrobial agents.</span></p><br />
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-03-24 15:14:48
 
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http://op.niscair.res.in/index.php/IJC/article/view/61730
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 3 (2022): Indian Journal of Chemistry-(IJC)
 
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