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Nano-therapeutic efficacy of green synthesized gold nanoparticles (gAuNPs) and its antibacterial efficacy

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Title Nano-therapeutic efficacy of green synthesized gold nanoparticles (gAuNPs) and its antibacterial efficacy
 
Creator Setia, Vivan Yagnik
Dangi, Kapil
Biswas, Largee
Singh, Priyanka
Verma, Anita Kamra
 
Subject Antibacterial activity
gAuNPs
Surface plasmon resonance
 
Description 455-460
We report the efficacy of the gold nanoparticles (AuNPs) synthesized using the leaf extracts of Syzygium cumini (common name Jamun) with auric chloride (AuCl4) which was used as both reducing and capping agent at room temperatures- 25°C. Synthesized AuNPs were characterized using UV-Vis spectroscopy indicating a peak in the range of 520-540 nM. The hydrodynamic radii measured by DLS clearly indicated the size of AuNPs in the range of 14-64 nM. The biological efficacy in terms of antimicrobial activity was assessed by the Kirby Bauer method, applied for both Gram-positive and Gram-negative bacteria such as Staphylococcus aureus and Escherichia coli, respectively. The Zone of inhibition (ZOI) diameter was found to be 4 mM and 3 mM in S. aureus and E. coli, as indicated by the bactericidal activity. Hence, AuNPs synthesized by green synthesis are proposed as economical, environment friendly with immense potential as an antibacterial agent and for drug delivery.
 
Date 2022-04-11T06:34:51Z
2022-04-11T06:34:51Z
2022-04
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscair.res.in/handle/123456789/59506
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJBB Vol.59(4) [April 2022]