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A COMPREHENSIVE REVIEW ON BENZIMIDAZOLE DERIVATIVES AND ITS BIOLOGICAL IMPORTANCE
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
A COMPREHENSIVE REVIEW ON BENZIMIDAZOLE DERIVATIVES AND ITS BIOLOGICAL IMPORTANCE
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| Creator |
M, SHANKAR
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| Subject |
Therapeutic Agents, Heterocyclic Compounds, Synthetic Products
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| Description |
Condensation of o-phenylene-diamine with formic acid is used in the synthesis of commercially available benzimidazole. N-riosyldimethyl benzimidazole is the most common benzimidazole compound found in nature, and it functions as an axial ligand for cobalt in vitamin B12. The benzimidazole and its derivatives are important therapeutic agents, such as antiulcer and anthelmintic drugs. Benzimidazole compounds also possess antimicrobial, antiviral, anticancer, anti-inflammatory, analgesic, and other pharmacological properties. The chemistry and pharmacological actions of substituted benzimidazoles are summarised in this article.
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| Date |
2022-04-18T04:32:55Z
2022-04-18T04:32:55Z 2012-01-26 |
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| Type |
Article
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| Identifier |
2582-6492 (Online); 0036-8512 (Print)
http://nopr.niscair.res.in/handle/123456789/59532 |
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| Language |
en
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| Publisher |
NIScPR-CSIR, India
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| Source |
SR Vol.59(04) [April 2022]
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