Record Details

Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy

DIR@IMTECH: CSIR-Institute of Microbial Technology

View Archive Info
 
 
Field Value
 
Title Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy
 
Creator Kalra, Rashi
Tiwari, Drishti
Dkhar, H Kitdorlang
Bhagyaraj, Ella
Kumar, Rakesh
Bhardwaj, Anshu
Gupta, Pawan
 
Subject QR Microbiology
 
Description Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up as adjuncts to drug therapies against drug resistant TB strains; however, there needs to be an urgent appraisal of host specific drug targets for improving their clinical management and to curtail disease progression. Presently, various host directed therapies (HDTs) exist (repurposed drugs, nutraceuticals, monoclonal antibodies and immunomodulatory agents), but these mostly address molecules that combat disease progression.
 
Publisher Informa healthcare
 
Date 2021-09-22
 
Type Article
PeerReviewed
 
Relation https://www.tandfonline.com/doi/abs/10.1080/08830185.2021.1990277?journalCode=iiri20
http://crdd.osdd.net/open/2951/
 
Identifier Kalra, Rashi and Tiwari, Drishti and Dkhar, H Kitdorlang and Bhagyaraj, Ella and Kumar, Rakesh and Bhardwaj, Anshu and Gupta, Pawan (2021) Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy. International reviews of immunology. ISSN 1563-5244