Free-radical scavenging and α-glucosidase inhibitory activities of pyrazoline and pyrazole heterocyclic compounds
NOPR - NISCAIR Online Periodicals Repository
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Title |
Free-radical scavenging and α-glucosidase inhibitory activities of pyrazoline and pyrazole heterocyclic compounds
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Creator |
Ramya, S
Anusha, K Tiwari, A K Raju, B China |
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Subject |
Pyrazolines
pyrazoles free-radical scavenging α-glucosidase inhibitory activity |
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Description |
399-404
A total of fifty pyrazolines 3a-y and pyrazoles 4a-y have been evaluated for their free-radical scavenging and α-glucosidase inhibitory activities. The pyrazolines 3e, 3h, 3p, 3s and pyrazole 4e have been identified as potent ABTS.+ free-radical scavengers. The thiophene substituted pyrazoline 3s has shown potent ABTS.+ free radical scavenging activity compared to thiophene substituted pyrazole 4s. Furanyl (4r), pyrazolyl (4t), 2-chloropyridinyl (4u-w), 2-chloroquinolinyl (4x) and 4-chlorocoumarin (4y) pyrazoles have displayed moderate ABTS.+ free-radical scavenging activity. Pyrazoline 3i and pyrazole 4b have shown moderate DPPH free-radical scavenging activity. |
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Date |
2022-04-19T06:36:25Z
2022-04-19T06:36:25Z 2022-04 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscair.res.in/handle/123456789/59545 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJC Vol.61(04) [April 2022]
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