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Pharmaceutical standardization and physicochemical characterization of traditional ayurvedic mineral drug red ochre roasted in cow‘s ghee (<em>Shuddha Gairik</em>)

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Title Statement Pharmaceutical standardization and physicochemical characterization of traditional ayurvedic mineral drug red ochre roasted in cow‘s ghee (<em>Shuddha Gairik</em>)
 
Added Entry - Uncontrolled Name CHAVAN, SANDEEP BHAGWAN; Bharatiya Sanskriti Darshan Trust's Integrated Cancer Treatment and Research Centre
Gupta, V S; Drug Standardization Laboratory, Bharatiya Sanskriti Darshan Trust‘s Integrated Cancer Treatment and Research Centre, Wagholi, Pune 412 207, India
Deshmukh, V V; Drug Standardization Laboratory, Bharatiya Sanskriti Darshan Trust‘s Integrated Cancer Treatment and Research Centre, Wagholi, Pune 412 207, India
Sardeshmukh, S P; Drug Standardization Laboratory, Bharatiya Sanskriti Darshan Trust‘s Integrated Cancer Treatment and Research Centre, Wagholi, Pune 412 207, India
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Uncontrolled Index Term Ferric oxide; Gairik; Kaolinite; Monograph; Red ochre; Roasting
 
Summary, etc. <p><em>Rasashastra</em> is a pharmaceutics branch of Ayurveda describing scientific methods to convert metals and minerals into bio-compatible formulations that are used individually or plant admixed to enhance their bioavailability and efficacy. In the present study, red ochre (<em>Gairik</em>) powder was processed in cow’s ghee by textual method of roasting. The steps of preparation and changes in the properties therein were documented and validated in triplicate batches to develop a monograph. Ayurvedic and basic tests were performed to determine the properties of <em>Shuddha</em> <em>Gairik</em>. The physical characterization included Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infra-red (FT-IR), Dynamic Light Scattering (DLS) and Thermo-gravimetric Analysis (TGA). Elemental composition was estimated by titration and gravimetric analysis while heavy metal limits were assessed using Inductively Coupled Plasma Optical Emission Spectrophotometry (ICPOES). This study depicted that crude red ochre, containing Kaolinite with high iron percentage, on roasting in cow’s ghee led to the formation of fatty acids adsorbed red ochre particles. The developed monograph will be a guideline to the Ayurvedic industry for precise formulation of <em>Shuddha Gairik</em>. This will help researchers for better understanding the importance of Ayurvedic methods of pharmaceutical preparations and carry out their mechanistic studies in various diseases.</p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2022-04-29 17:11:44
 
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http://op.niscair.res.in/index.php/IJTK/article/view/31007
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 21, ##issue.no## 2 (2022): Indian Journal of Traditional Knowledge
 
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