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<p class="Standard"><em>In vitro</em> anticancer activity of medicinal plants of Himalayan region</p>

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Title Statement <p class="Standard"><em>In vitro</em> anticancer activity of medicinal plants of Himalayan region</p>
 
Added Entry - Uncontrolled Name Bhardwaj, Pallavi ; DGCN COVAS, CSKHPKV, Palampur, H.P.
Thakur, Shraya ; Department of Veterinary Pharmacology and Toxicology, DGCN College of Veterinary and Animal Sciences, CSK HPKV, Palampur, Himachal Pradesh 176 062, India
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Uncontrolled Index Term Anticancer, Camellia sinensis, Cytotoxicity, Himalayan region, SRB assay
 
Summary, etc. <p>Plant-derived products have gained attention over the past few years due to their potential as novel cancer preventive and therapeutic agents. Himalayan region is known for its vast  reserve  of  natural  resources. The present study was planned with the objective to explore the anticancer potential of plants of Himalayan region. Total twenty lyophilized plant extracts were prepared after extraction with 70 % ethanol. All plant extracts were evaluated for percent cytotoxicity against LC-540 Leydig Cell Testicular Tumor cell line (rats) at various concentration levels (20, 50, 100 and 200 µM) and at different time of incubation (24, 48, 72 h). The results revealed that the aqua-ethanolic extract of leaves of <em>Camellia sinensis</em> exhibited maximum anticancer activity among all twenty extracts screened, with 42.74 ± 4.63 % and 68 ± 1.74 % cytotoxicity at 100 µM and 200 µM concentration respectively, followed by<em> Lantana camara, Tinospora cordiofolia </em>and<em> Cedrus deodara</em>. Further<em> </em>exploration of <em>in vivo</em> antineoplastic effects and probable mechanism of action of its potent phyto-constituents could be highly useful in developing an effective herbal formulation in cancer therapeutics.</p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2022-04-29 17:11:44
 
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http://op.niscair.res.in/index.php/IJTK/article/view/39804
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 21, ##issue.no## 2 (2022): Indian Journal of Traditional Knowledge
 
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