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Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study

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Title Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study
 
Creator Dastghaib, Sanaz
Koohpeyma, Farhad
Khazayel, Saeed
Gholizadeh, Fatemeh
Pour, Soheila Mansoor
Mokaram, Pooneh
Noorafshan, Ali
 
Subject Blood glucose
Candyleaf
Diabetes mellitus
Oxidative stress
 
Description 299-307
In recent years, among antidiabetic medicinal herbs, Stevia received a lot of attention due to its diverse therapeutic
applications. Despite extensive reports on the effects of Stevia on the pancreas, its molecular mechanism is not clear yet. In
this study, we investigated the protective and preventive effects of oral extracts of Stevia on the pancreas through the
stereological methods in streptozocin (STZ) induced diabetic rats. Thus, 66 adult male rats were assigned to six groups
(n = 11) viz., healthy control, healthy Stevia (400 mg /kg), diabetic-control, diabetic-metformin (500 mg/kg), diabetic-Stevia
and pre-Stevia-diabetic group. Treatment with Stevia significantly reduced fasting blood sugar (FBS) and MDA compared to
the diabetic control group (P
 
Date 2022-05-02T11:27:05Z
2022-05-02T11:27:05Z
2022-05
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscair.res.in/handle/123456789/59642
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.60(05) [May 2022]