Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study
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Title |
Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study
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Creator |
Dastghaib, Sanaz
Koohpeyma, Farhad Khazayel, Saeed Gholizadeh, Fatemeh Pour, Soheila Mansoor Mokaram, Pooneh Noorafshan, Ali |
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Subject |
Blood glucose
Candyleaf Diabetes mellitus Oxidative stress |
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Description |
299-307
In recent years, among antidiabetic medicinal herbs, Stevia received a lot of attention due to its diverse therapeutic applications. Despite extensive reports on the effects of Stevia on the pancreas, its molecular mechanism is not clear yet. In this study, we investigated the protective and preventive effects of oral extracts of Stevia on the pancreas through the stereological methods in streptozocin (STZ) induced diabetic rats. Thus, 66 adult male rats were assigned to six groups (n = 11) viz., healthy control, healthy Stevia (400 mg /kg), diabetic-control, diabetic-metformin (500 mg/kg), diabetic-Stevia and pre-Stevia-diabetic group. Treatment with Stevia significantly reduced fasting blood sugar (FBS) and MDA compared to the diabetic control group (P |
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Date |
2022-05-02T11:27:05Z
2022-05-02T11:27:05Z 2022-05 |
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Type |
Article
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Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscair.res.in/handle/123456789/59642 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJEB Vol.60(05) [May 2022]
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