Bombax ceiba calyces regulate carbohydrate and lipid digesting enzyme’s actions, display insulin sensitizing and antioxidant activities in vitro: A nutritional and phytochemicals examination
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Title |
Bombax ceiba calyces regulate carbohydrate and lipid digesting enzyme’s actions, display insulin sensitizing and antioxidant activities in vitro: A nutritional and phytochemicals examination
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Creator |
Anusha, Komati
Anand, Ajay Babu, Katragadda Suresh Tiwari, Ashok Kumar |
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Subject |
α-amylase
α-glucosidase Antioxidant property Bombax ceiba calyces DNA damage Lipase Nutritional analysis PTP1β inhibition |
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Description |
323-331
Calyces of Bombax ceiba (Śālmali, शाल्मली) are used as vegetable by traditional Indian folks. However, scientific investigations for this vegetable are not available in literature. This research presents nutritional and phytochemicals composition in raw calyxes’ powder and antihyperglycemic, antihyperlipidemic, insulin-sensitizing and, antioxidant properties in aqueous methanolic extract of calyx applying various in vitro methods. Calyx powder displayed rich source of macro- and micronutrients with energy value 322 Kcal. /100 g. Aqueous methanol extract of calyces exhibited potent antihyperglycemic activities by inhibiting pancreatic α-amylase and intestinal α-glucosidase enzymes, antihyperlipidemic by inhibiting pancreatic lipase and insulin sensitizing property by inhibiting PTP1β. It was found to be potent scavenger of chemical and physiological free radicals and, presented antioxidant activities by preventing H2O2 induced erythrocytes membrane lipid peroxidation and hemolysis. It also prevented H2O2 induced genomic DNA damage. The calyx powder presented 979 μg/100 g total antioxidant value. This report presents original analysis of nutritional and phytochemical composition along with biological activities in B. ceiba calyx. |
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Date |
2022-05-04T10:40:48Z
2022-05-04T10:40:48Z 2022-04 |
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Type |
Article
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Identifier |
0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/59659 |
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Language |
en
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Relation |
Int Cl.22: A61K 36/00, A61Q 19/08
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Publisher |
NIScPR-CSIR, India
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Source |
IJTK Vol.21(2) [April 2022]
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