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HYSSOP and POLIUM could help to prevent COVID-19 in high-risk population: The results of a parallel randomized placebo-controlled field trial

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Title HYSSOP and POLIUM could help to prevent COVID-19 in high-risk population: The results of a parallel randomized placebo-controlled field trial
 
Creator Fazlju, Seyyed Mohammad Bagher
Heris, Javad Ahmadian
Farshbaf-Khalili, Azizeh
Khodadadi, Khodadad
Mohammadi, Ahad Banagozar
Shahabi, Parviz
Dorosti, Abbasali
Hamishekar, Hamed
Naghipour, Bahman
Pourfathi, Hojjat
Zahednia, Mohammad
Valizadeh, Einollah
Ranjbari, Yones
Zarei, Ahad
Sakaki, Ehsan
Ghassab-Abdollahi, Nafiseh
Salehi-Pourmehr, Hanieh
Safiri, Saeid
 
Subject COVID-19
HYSSOP
Medicinal herbs
POLIUM
Prevention
 
Description 243-253
This study was conducted to evaluate the effect of HYSSOP (composed of Hyssopus officinalis L., Echium amoenum Fisch & C. A. Mey and Glycyrrhiza glabra L.) and POLIUM (contained Teucrium polium L., Cuscuta epithymum Murr and Cichorium intybus L.) combined distilled herbal medicines compared to placebo in the prevention of COVID-19. This is a double-blind parallel placebo-controlled field trial conducted on 751 asymptomatic individuals whose one of the family members recently had a positive RT-PCR test for COVID-19. They were divided into three groups including POLIUM, HYSSOP and placebo using random blocks with a 1:1:1 allocation ratio. Participants received daily 5 cc (under 12 years) or 10 cc (over 12 years) of allocated oral medications for 20 days. The primary outcome was the frequency of positive RT-PCR test among participants who became symptomatic. The mean age of participants was 36.6. Nineteen participants get infected by COVID-19 during the intervention; fifteen of them belonged to the placebo and four to the POLIUM group. Fisher's exact test indicated significant differences between HYSSOP and placebo (p
 
Date 2022-05-04T11:04:22Z
2022-05-04T11:04:22Z
2022-04
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/59669
 
Language en
 
Relation Int Cl.22: A61K 36/00, A6iK 36/53, A61K 39/215
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.21(2) [April 2022]