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Evaluation of pharmacological and catalytic activity of CuO and Zn doped CuO nanoparticles<br />

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Title Statement Evaluation of pharmacological and catalytic activity of CuO and Zn doped CuO nanoparticles<br />
 
Added Entry - Uncontrolled Name Saranya, Rishikesan ; Centre for Research and Evaluation, Department of Chemistry, Bharathiar University, Coimbatore - 641 046
Ali, Muhamath Basha Mubarak; Chikkaiah Naicker College, Erode.
Jeyalakshmi, Kumaramangalam ; M.Kumarasamy College of Engineering, Karur, Tamilnadu
Nil
 
Uncontrolled Index Term Material science; nanomaterial
CuO, Zn-CuO NPs, Antibacterial, Antioxidant, Cytotoxicity, MCF7, A549
 
Summary, etc. CuO and Zn doped CuO nanoparticles (Zn-CuO NPs) with varying concentration i.e., ZnxCu<sub>1−x</sub>O (where x = 0, 0.5, 1, and 1.5%) have been prepared via microwave assisted method. The spheroid structure of CuO NPs and the nanorod structure of ZnCuO NPs have been determined using High Resolution Scanning Electron Microscopy (HR-SEM) analysis. Elemental analysis has been carried out using Energy Dispersive X-ray Analysis (EDAX). The particle size and surface area of CuO and Zn-CuO NPs have been confirmed by Brunauer–Emmett–Teller (BET) method. The antibacterial studies have been revealed that Zn<sub>(1.5%)</sub>-CuO NPs exhibited maximum zone of inhibition (19-29 mm) against the tested four bacterial strains. Zn-CuO NPs have been displayed robust action of antibacterial activity with minimum inhibitory concentration (MIC) of 0.09 µM against Campylobacter coli (C. Coli). DPPH and H2O2 radical scavenging assay investigation have been revealed that the significant scavenging activity has showed by Zn<sub>(1.5%)</sub>-CuO. The in vitro cytotoxicity evaluation of synthesized material against human breast (MCF7) and human lung (A549) cancer cell lines have been demonstrated that Zn<sub>(1.5%)</sub>-CuO NPs exhibited better cytotoxic activity against MCF7 cell lines (97.5% cell death) than A549 cell lines (90% cell death).
 
Publication, Distribution, Etc. Indian Journal of Engineering and Materials Sciences (IJEMS)
2022-05-11 17:13:21
 
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http://op.niscair.res.in/index.php/IJEMS/article/view/44764
 
Data Source Entry Indian Journal of Engineering and Materials Sciences (IJEMS); ##issue.vol## 29, ##issue.no## 1 (2022): IJEMS-FEBRUARY 2022
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJEMS/article/download/44764/465542937
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http://op.niscair.res.in/index.php/IJEMS/article/download/44764/465542941
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http://op.niscair.res.in/index.php/IJEMS/article/download/44764/465542946
http://op.niscair.res.in/index.php/IJEMS/article/download/44764/465542947
 
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