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Antioxidant, antibacterial, and antifungal activity of Hymenochaete rubiginosa

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Title Antioxidant, antibacterial, and antifungal activity of Hymenochaete rubiginosa
 
Creator İnci, Şule
Sevindik, Mustafa
Kırbağ, Sevda
Akgül, Hasan
 
Subject Antimicrobial
Antioxidant
Hymenochaete rubiginosa
Medicinal mushroom
Oxidant.
 
Description 67-71
The use of fungi in alternative medicine and their use as pharmacological agents is gradually increasing today.
Hymenochaete rubiginosa (Dicks.) Lév, locally known as Crust, is a species that belongs to the Polyporales family. In this
study, it was aimed to determine the antimicrobial and antioxidant activity of H. rubiginosa extracts obtained from ethanol
solvent. Its antimicrobial activity has been determined using the microdilution (MIC) method. In this study, bacteria such as
Staphylococcus aureus ATCC 29213, Staphylococcus aureus MRSA ATCC 43300, Enterococcus faecalis ATCC 29212.
Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853 and Acinetobacter baumannii ATCC 19606 and
Candida albicans ATCC 10231, Candida krusei ATCC 34135 and Candida glabrata ATCC 9003 have been used as fungi.
Total antioxidant level (TAS), total oxidant level (TOS) and oxidative stress index (OSI) values were calculated for
antioxidant activity. According to the results obtained, it has been determined that the ethanol extract of H. rubiginosa
showed antimicrobial effect against test microorganisms at concentrations of 25-200 μg/mL. The TAS value of
H. rubiginosa has been determined as 6.313±0.050 mmol/L, TOS value as 14.358±0.202 μmol and OSI value as
0.227±0.002. As a result, it has been determined that H. rubiginosa can be used as an antioxidant and antimicrobial agent in
pharmacological designs.
 
Date 2022-05-12T08:58:38Z
2022-05-12T08:58:38Z
2022-03
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/59695
 
Language en
 
Relation Int. cl. (2021.01)–A61K 36/00, A61K 36/06, A61P 31/00, A61 39/00
 
Publisher NIScPR-CSIR, India
 
Source IJNPR Vol.13(1) [March 2022]