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<p>Synthesis, characterization and antioxidant activities of novel <em>N</em>-substituted pyrazoline derivatives bearing 3-benzo[b]thiophene and 5-styryl substituents</p>

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Title Statement <p>Synthesis, characterization and antioxidant activities of novel <em>N</em>-substituted pyrazoline derivatives bearing 3-benzo[b]thiophene and 5-styryl substituents</p>
 
Added Entry - Uncontrolled Name Krishnan, Radhakrishnan ; Saraswathi Narayanan College of Arts and Science, Madurai Kamaraj University, Madurai 625 022, Tamil Nadu, India
Pandy, Karthik Manikandan; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
Pandy, Karthik Manikandan; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
Paratharaj, Senthil Kumar; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
Paratharaj, Senthil Kumar; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
Ray, Uttam Kumar; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
Ray, Uttam Kumar; Solara Active Pharma Sciences Limited, R&D Centre, No. 27, Melakottaiyur (PO), Chennai 600 100, Tamil Nadu, India
 
Uncontrolled Index Term Pyrazoline, benzo[b]thiophene, N-substituted pyrazolines, antioxidant activity, trifluoromethyl cinnamaldehyde
 
Summary, etc. <p>The new series of N-substituted pyrazoline derivatives bearing benzo[b]thiophene and styryl with trifluoromethyl substitution at <em>para-</em> and <em>meta-</em> positions were synthesized. The structures of newly synthesized compounds were characterized by UV, IR, NMR, Mass and single crystal XRD (SCXRD) and had been screened for antioxidant activity. The <em>in vitro</em> antioxidant activities screening revealed that hydroxyl radical scavenging (HRS) activities of compounds <strong>3c, 3f, 4a, 4e, 4f, 5c, 5d 5e </strong>and<strong> 5g</strong> are stronger than the other compounds and the compound <strong>5g</strong> shows much better antioxidant activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-07-18 17:03:37
 
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http://op.niscair.res.in/index.php/IJC/article/view/64622
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 7 (2022): Indian Journal of Chemistry-(IJC)
 
Language Note en