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<p>Antibacterial and wound healing efficacy of <em>Chromolaena odorata</em> treated dressings</p>

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Title Statement <p>Antibacterial and wound healing efficacy of <em>Chromolaena odorata</em> treated dressings</p>
 
Added Entry - Uncontrolled Name Resmi, G ; 1Department of Design, Manipal School of Architecture and Planning, Manipal Academy of Higher Education, Manipal 576 104, India
Amsamani, S ; 2Department of Textiles and Clothing, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore 641 043, India
 
Uncontrolled Index Term Antibacterial textiles;Bioactive wound dressings;Chromolaena odorata;Cytotoxicity;In vivo wound healing;Spun lace viscose
 
Summary, etc. <p class="Abstract" style="text-align: justify;">This paper reports the characteristics of viscose fabric treated with the extracts of <em>Chromolaena odorata, </em>traditionally used for healing the wounds. <em>C. odorata</em> extracts (5%) are nano-sprayed and applied on spun lace viscose fabric using an ultrasonic atomiser and antibacterial competence is optimised for <em>S. aureus</em> and <em>E. coli</em>. The wound healing potential of the <em>C. odorata</em> treated dressing and histopathological analysis of the wound tissues have been studied <em>in vivo</em> on <em>Albino Wistar</em> rats and compared with wound without any dressings, chitosan treated dressing, chitosan and <em>C. odorata</em> treated dressing along with the commercial silver bandage. The FTIR analysis of the phytochemicals finished fabric indicates the presence of phenolic group. Cytotoxicity test reveals 22% cytotoxicity and 78% cell viability with mild toxicity. Shelf life discloses the decrease in antibacterial efficiency after third and fourth week. Curing of <em>C. odorata</em> extracts treated fabric inversely affects the antibacterial efficiency, and sterilisation reports 46.7% <em>E.coli</em> reduction after one hour. The fabricated wound dressings are found to have good wound healing efficiency as compared to commercial silver bandage. The histopathological analysis reveals complete healing of wounds after 21 post wound healing days. The study proves that the phytochemicals can be imparted on spun lace viscose fabric for antibacterial and wound healing application to a certain period of time.</p>
 
Publication, Distribution, Etc. Indian Journal of Fibre & Textile Research (IJFTR)
2022-07-27 16:42:38
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJFTR/article/view/64920
 
Data Source Entry Indian Journal of Fibre & Textile Research (IJFTR); ##issue.vol## 47, ##issue.no## 1 (2022): Indian Journal of Fibre & Textile Research
 
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