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A new Ca(II) coordination polymer: Structural characterization and treatment activity on childhood asthma

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Title A new Ca(II) coordination polymer: Structural characterization and treatment activity on childhood asthma
 
Creator Yuan, Wenxiao
Cai, Luliang
Tang, Yanjiao
Fu, Binsha
Wang, Ling
 
Subject BALF
Coordination polymer
Childhood asthma
RT-PCR
 
Description 325-329
In the present study, a 3D coordination polymer with the chemical composition of[(CH3)2NH2][Ca(tcpbH)(H2O)] (1) has
been solvothermally obtained from a rigid tetracarboxylic acid ligand tetrakis-(4-carboxyphenyl)benzene (H4tcpb) and
alkaline-earth ion CaII. Complex 1 has been well studied via Fourier-transform infrared spectroscopy, elemental analysis
(EA), TG analysis and single-crystal X-ray diffraction analysis. Its application values on the childhood asthma were
determined and the internal principle has been discussed simultaneously. Firstly, the ELISA is utilized to measure the
content of inflammatory cytokines released into the Broncho alveolar lavage fluid (BALF) after compound treatment. In
addition to this, the real time RT-PCR was conducted to measure the relative expression levels of NF-κB signaling pathway
in the alveolar epithelial cells.
 
Date 2022-06-27T09:13:46Z
2022-06-27T09:13:46Z
2022-05
 
Type Article
 
Identifier 0975-0991 (Online); 0971-457X (Print)
http://nopr.niscpr.res.in/handle/123456789/59928
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJCT Vol.29(3) [May 2022]