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Carcinoembryonic antigen (CEA) and other surrogate inflammatory biomarkers in COVID-19

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Title Carcinoembryonic antigen (CEA) and other surrogate inflammatory biomarkers in COVID-19
 
Creator Sharma, Anjali
Maksane, Shalini
Das, Jhuma
Yadav, Dharamveer
Tomo, Sojit
Sharma, Rajeev
Kumar, Sudhir
Cheirmaraj, K
Pai, Vidya
Parab, Kalpana
 
Subject Acute respiratory distress syndrome
Biochemical parameters
CEA
Inflammatory markers
 
Description 667-674
It has been two years since the global outbreak of the highly contagious and deadly corona virus disease (COVID-19)
caused by SARS-CoV-2 first emerged in China. Since then, various diagnostic, prognostic and treatment strategies
undertaken to address the pandemic have been dynamically evolving. Predictive and prognostic role of various biomarkers
in COVID-19 has been a subject of intense exploration. We aimed to determine the association of Carcinoembryonic antigen
(CEA) and various surrogate inflammatory biomarkers with the severity of COVID-19 disease. This retrospective cohort
study was carried out on 98 patients admitted in Jaypee Hospital, Noida with COVID-19 disease. Information regarding
demographics, laboratory parameters and clinical history was collected from Hospital Information System. Serum levels of
CEA and other biomarkers such as Neutrophil-lymphocyte ratio (NLR), C-reactive protein (CRP), Interleukin-6 (IL-6),
Ferritin, and Procalcitonin (PCT) were assessed. Correlation analyses were performed between the parameters and acute
respiratory distress syndrome (ARDS) stages. Logistic regression and ROC curve analysis were performed to assess the
various parameters for distinguishing COVID-19 patients requiring ICU admission. Mean hospital stay, NLR, CEA, IL-6,
CRP, Ferritin (P
 
Date 2022-07-01T11:02:02Z
2022-07-01T11:02:02Z
2022-06
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscpr.res.in/handle/123456789/60009
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJBB Vol.59(6) [June 2022]