Record Details

Hypervalent iodine mediated solid state synthesis of 2-aryl-5- [2-(3,4,5-trimethoxyphenyl)[1,8]naphthyridin- 3-yl]-1,3,4-oxadiazoles

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Hypervalent iodine mediated solid state synthesis of 2-aryl-5- [2-(3,4,5-trimethoxyphenyl)[1,8]naphthyridin- 3-yl]-1,3,4-oxadiazoles
 
Creator Challa, Pradeep Kumar
Ega, Jagadeesh Kumar
 
Subject 1,8-Naphthyridine
PhI(OAc)2
SiO2-FeCl3
Oxadiazoles
 
Description 635-639
The hydrazones 5 on oxidative cyclization of with [PhI(OAc)2] in the solid state at room temperature under grinding
conditions has furnished the respective 2-aryl-5-[2-(3,4,5-trimethoxyphenyl)[1,8]naphthyridin-3-yl]-1,3,4-oxadiazoles 6 in
good yields without any undesirable byproducts. The purity of the products is high. The method is preoperatively
convenient, useful and environmentally benign. The experimental procedure is very simple and avoids sophistication. The
most probable mechanism of above transformation is suggested. The structure of compounds 5 and 6 has been confirmed by
their spectroscopic(IR, 1H NMR and MS) and analytical data.
 
Date 2022-07-05T10:43:20Z
2022-07-05T10:43:20Z
2022-06
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60031
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.61(06) [June 2022]