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Pharmacological evaluation of some synthesized thiazolidinone derivatives containing Mannich base of sydnone and p-phenylenediamine

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Title Pharmacological evaluation of some synthesized thiazolidinone derivatives containing Mannich base of sydnone and p-phenylenediamine
 
Creator Savant, Suchitra S
Vashi, Parikshit I
Gamit, Elit A
Patel, Keshav C
Patel, Paresh S
 
Subject Thiazolidinone
Mannich base
sydnone
antimicrobial
 
Description 591-598
A series of 4-thiazolidinone derivatives incorporating Mannich base of 3-(3-nitrophenyl)sydnone have been
synthesized by conventional routes and evaluated for their antimicrobial activities against E. coli, P. aerugenosa, S. aureus,
S. pyogenus, C. albicans, A. niger and A. clavatus. Most of the compounds show moderate to very good biological activity.
The structures of synthesized compounds 7a-j have been elucidated by C, H, and N analysis, FT-IR, 1H and 13C NMR and
mass spectrometry.
 
Date 2022-07-05T11:00:59Z
2022-07-05T11:00:59Z
2022-06
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60036
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.61(06) [June 2022]