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Synthesis, characterization and antioxidant activities of novel N-substituted pyrazoline derivatives bearing 3-benzo[b]thiophene and 5-styryl substituents

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Title Synthesis, characterization and antioxidant activities of novel N-substituted pyrazoline derivatives bearing 3-benzo[b]thiophene and 5-styryl substituents
 
Creator Krishnan, Radhakrishnan
Pandy, Karthik Manikandan
Paratharaj, Senthil Kumar
Ray, Uttam Kumar
 
Subject Pyrazoline
benzo[b]thiophene
N-substituted pyrazolines
antioxidant activity
trifluoromethyl cinnamaldehyde
 
Description 703-716
The new series of N-substituted pyrazoline derivatives bearing benzo[b]thiophene and styryl with trifluoromethyl
substitution at para- and meta- positions were synthesized. The structures of newly synthesized compounds were
characterized by UV, IR, NMR, Mass and single crystal XRD (SCXRD) and had been screened for antioxidant activity. The
in vitro antioxidant activities screening revealed that hydroxyl radical scavenging (HRS) activities of compounds 3c, 3f, 4a,
4e, 4f, 5c, 5d 5e and 5g are stronger than the other compounds and the compound 5g shows much better antioxidant activity.
 
Date 2022-07-15T11:08:55Z
2022-07-15T11:08:55Z
2022-07
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60114
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.61(07) [July 2022]