Record Details

Fingerprinting of Sahaj Vati, additive for natural lovastatin production

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Fingerprinting of Sahaj Vati, additive for natural lovastatin production
 
Creator Yadav, Kapil Deo
 
Subject Aspergillus flavus
Fimger printing
Lovastatin
Sahaj Vati
 
Description 505-510
The lovastatin has been used in hypercholesterolemia and heart diseases for therapeutic as well as preventative purposes and
it is naturally obtained from filamentous fungi such as Aspergillus through biotechnological approach. The additives in fungal
media which enhances the fungal growth should also increase the production of lovastatin. Finger printing of
Sahaj Vati, a herbo-mineral formulation comprising mixture of Plumbago zeylanica, Curcuma longa, Shilajeet, Commiphora
mukul and Clerodendrum phlomidis powder to be added in medium for fungal growth. The fungal growth activity of both
batches of Sahaj Vati was tested for fungal isolate of A. flavus by contact measure through hyphal development restraint test
utilizing Potato dextrose agar (PDA) and SMKY medium followed by chromatographic and different techniques for
standardization. Sahaj Vati has lower antifungal index & increased the fungal biomass and separation of compound was higher
in mobile phase Benzene: Ethyl acetate: Pyridine: 5:4.9:0.1 & Hexane: Chloroform: Pyridine: 2.7:1. Sahaj Vati increased the
growth and biomass of A. flauvs which may be used for natural production of lovastatin.
 
Date 2022-07-28T12:23:36Z
2022-07-28T12:23:36Z
2022-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/60205
 
Language en
 
Relation Int Cl.22: A61K 9/00, A61K 36/00, A61K 45/06
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.21(3) [July 2022]