Record Details

Local and systemic effects of adrenomedullin after intestinal ischemia reperfusion

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Local and systemic effects of adrenomedullin after intestinal ischemia reperfusion
 
Creator Oyar, Eser Oz
Yildirim, Zuhal
Pampal, Arzu
Ilhan, Ayse Sebnem
Unlu, Nese Lortlar
 
Subject Inflammation
Intestinal ischemic reperfusion injury
Oxidative stress
 
Description 580-586
Adrenomedullin (AM) is a peptide proven to increase cellular tolerance to hypoxia and oxidative stresss and contribute angiogenesis. Despite its known therapeutic effects on myocardial, renal or spinal ischemic reperfusion injuries, its local and systemic effects on intestinal ischemic reperfusion injury still remain unknown. This study aims to demonstrate the local and systemic effects of AM on Intestinal Ischemic Reperfusion Injury (I-IRI) demonstrated in rats. Thirty male rats were randomly allocated to five groups: Control, Adrenomedullin (AM), Intestinal Ischemic Reperfusion Injury (I-IRI), Adrenomedullin and Intestinal Ischemic Reperfusion Injury (AM+I-IRI), and Intestinal Ischemic Reperfusion Injury and Adrenomedullin (I-IRI+AM). Blood and tissue samples were obtained for biochemical and histopathological evaluation. The results were expressed as mean±SEM and, P
 
Date 2022-08-01T11:42:57Z
2022-08-01T11:42:57Z
2022-08
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/60242
https://doi.org/10.56042/ijeb.v60i08.51008
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJEB Vol.60(08) [AUG 2022]