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<p style="text-align: justify;">Disease modifying activity of methanolic extract of <em>Colchicum luteum </em>against experimental gout in broiler chicken</p>

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Title Statement <p style="text-align: justify;">Disease modifying activity of methanolic extract of <em>Colchicum luteum </em>against experimental gout in broiler chicken</p>
 
Added Entry - Uncontrolled Name Ali, Rayeesa ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Kamil, S A ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Mir, M S ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Shah, S A ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Wani, B M ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Adil, S ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
Shafi, M ; Division of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e-Kashmir University of Agricultural Science & Technology (SKUAST-K), Srinagar 190006, Jammu and Kashmir, India
 
Uncontrolled Index Term Biochemical analysis; Colchicum luteum; Gout; Haematology; Sodium bicarbonate.
 
Summary, etc. <p style="text-align: justify;"><em>Colchicum luteum</em>, a Himalayan herb has been found associated with immense pharmaceutical properties. The present study was aimed to study the protective effect of methanolic extract of <em>C. luteum </em>against the haemato-biochemical alterations due to sodium bicarbonate induced gout in broiler chicken. A total of 72 day old broiler chicks of average body weights 178±20.8 g were divided into 6 groups (I to VI, n=12). Group I served as vehicle-treated control and was given drinking water by oral gavage. Group II and III were given sodium bicarbonate @ 2.5 and 5% respectively in drinking water. Group IV and V were provided with 2.5 and 5% sodium bicarbonate along with <em>C. luteum </em>extract @ 50 mg/kg body weight respectively. Group VI served as treatment control and was given <em>C. luteum </em>extract @ 50 mg/kg body weight alone. Haematological and biochemical analysis revealed a significant increase in haematological parameters (Hb, PCV, TEC, TLC, and heterophil) and biochemical parameters (AST, ALT, uric acid, BUN, creatinine, total protein and albumin) in sodium bicarbonate intoxicated groups. All these parameters however, were comparatively reduced in the birds given <em>C. luteum </em>extract. Also, heterophil and monocyte counts were decreased significantly in group VI birds, supplemented with <em>C. luteum </em>extract only with no adverse effect on health of birds. The results from the present study establish the protective role of <em>C. luteum </em>extract against sodium bicarbonate induced haematological and biochemical alterations.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2022-08-13 01:04:42
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/41191
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 13, ##issue.no## 2 (2022): June 2022
 
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